The pattern of copper release in copper-based nanoparticles regulates tumor proliferation and invasiveness in 3D culture models
Jose I. García-Peiro, Paula Guerrero-López, Felipe Hornos, José L. Hueso, J. Manuel García-Aznar, Jesús Santamaría
Small Sci. 2024, 4, 2400206
Abstracts: Cancer is a leading cause of death worldwide. Glioblastoma (GBM) is a major challenge in oncology due to its highly invasive nature and limited treatment options. GBM’s aggressive migration beyond tumor margins and rapid tumor growth hinders success in patient treatment. Localized therapeutic delivery, such as the use of transition metals like copper, is highlighted as a novel therapeutic agent for many potential biomedical
